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Tamona 20mg Tablet 10pcs
Tamoxifen 20mg
- Treatment of Breast Cancer
- Management of Anovulatory Infertility
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✅ Description:
Tamoxifen (Tamona) is a non-steroidal, triphenylene-based medication with both estrogen antagonists and agonist effects, depending on the tissue.
- The mechanism in Breast Cancer: Acts as an antioestrogen at the tumor site by blocking estrogen receptors, thereby inhibiting tumor growth.
- Bone Health: Maintains bone mineral density in postmenopausal women due to its estrogen agonist-like activity on bones.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Dosage & Administration of Tamona 20
- Breast Cancer: 20 mg daily.
- Anovulatory Infertility:
- 20 mg daily on days 2-5 of the menstrual cycle.
- The dose may increase to 40 mg or 80 mg in subsequent cycles if needed.
- For irregular cycles, start the first course on any day, with subsequent courses 45 days later or on day 2 if menstruation occurs.
Always follow a registered physician's advice for dosage.
✔️ Side Effects of Tamona 20
Common:
- Hot flushes
- Vaginal bleeding or discharge
- Pruritus vulvae
- Tumor flare
- Gastrointestinal disturbances (nausea, vomiting, diarrhea)
- Fluid retention
- Headache
Less Common/Severe:
- Dermatological: Skin rashes (e.g., erythema multiforme, Stevens-Johnson syndrome).
- Blood: Leucopenia, thrombocytopenia, or neutropenia (occasionally severe).
- Visual: Corneal changes, retinopathy, cataracts.
- Reproductive: Uterine fibroids, endometrial hyperplasia, cystic ovarian swelling.
- Thromboembolic Events: Deep vein thrombosis, pulmonary embolism.
- Liver: Elevated liver enzymes, fatty liver, cholestasis, hepatitis.
- Metabolism: Elevated triglyceride levels (rarely leading to pancreatitis).
✔️ Interactions
- Anticoagulants: Co-administration with coumarin-type anticoagulants may increase their effects. Close monitoring is recommended.
- With Cytotoxic Agents: Combined use may heighten the risk of thromboembolic events.
✔️ Contraindications
- Pregnancy: Tamona must not be used due to potential risks to the fetus, including birth defects and fetal death.
- Allergic Reactions: Avoid use in individuals with hypersensitivity to Tamoxifen or its components.
✔️ Pregnancy & Lactation
- Pregnancy: Contraindicated. May cause harm to the fetus.
- Lactation: Not recommended, as it is unknown if Tamoxifen is excreted in human milk.
✔️ Precautions & Warnings
- Common in premenopausal women undergoing breast cancer treatment.
- Increased risk due to the estrogen-like effect of Tamona. Any abnormal gynecological symptoms, especially vaginal bleeding, should be promptly investigated.
- Second Primary Tumors is Rare but reported. The clinical relevance is unclear.
- Women must use barrier or nonhormonal contraceptives during treatment and for two months after stopping the medication.
✔️ Storage
- Store at 20-25°C.
- Protect from light.
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
